![]() The primary finding was a significant positive association between serum TSH and total and LDL cholesterol and triglycerides. Cholesterol levels were not significantly different between boys and girls, nor between children and adolescents. Over 95% of the total sample had serum TSH levels in the reference range. The average age was 7.4 years in children and ~14.4 years in adolescents. A total 6622 children (age range, 3 to 10 years) and 6134 adolescents (age range, 11 to 17 years) were studies. This study measured serum TSH and lipid levels, including total cholesterol, LDL cholesterol (bad cholesterol), HDL cholesterol (good cholesterol) and triglycerides in patients identified from the German Health Interview and Examination Survey for Children and Adolescents between 2003 to 2006. Witte T et al Association between serum thyroid-stimulating hormone levels and serum lipids in children and adolescents: a population-based study of German youth. The objective of this study was to test this association between hypothyroidism and cholesterol levels in children and adolescents using a large German population-based study sample. The few studies testing an association between thyroid function and cholesterol levels among children and adolescents are limited by their small sample sizes. This association between hypothyroidism and high cholesterol levels has been demonstrated in several large studies, most of which involved adult patients. Thyroid hormone has a direct effect on cholesterol levels, which increase as the TSH increases and hypothyroidism develops. TSH: thyroid stimulating hormone - produced by the pituitary gland that regulates thyroid function also the best screening test to determine if the thyroid is functioning normally. Examples of blood lipids include cholesterol, HDL (“good) cholesterol, LDL (“bad”) cholesterol and triglycerides. Lipids: the general term used to describe fat molecules in the blood. Treatment requires taking thyroid hormone pills. Hypothyroidism: a condition where the thyroid gland is underactive and doesn’t produce enough thyroid hormone. ![]()
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